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methyl 3-chloro-2-{3-[(2,5-dihydroxy-4-methoxyphenyl)amino]-3-oxopropyl}-4,6-dihydroxybenzoate
- Development stage
- Unknown
- Modality
- Small Molecules
01
Overview
Methyl 3-chloro-2-{3-[(2,5-dihydroxy-4-methoxyphenyl)amino]-3-oxopropyl}-4,6-dihydroxybenzoate is a synthetic small molecule belonging to the class of p-hydroxybenzoic acid alkyl esters. It has a molecular formula of C18H18ClNO8 and a molecular weight of approximately 411.8 g/mol[1][2]. The compound is considered experimental and is not approved for clinical use in any country[2]. Its primary known biological activity is as an inhibitor of heat shock protein HSP90-beta (HSP90AB1), suggesting potential utility in modulating protein folding and stress response pathways relevant to cancer or other diseases involving proteostasis[2]. No marketed products or clinical indications are currently associated with this compound.
- Other names
- methyl 3-chloro-2-(3-((2,5-dihydroxy-4-methoxyphenyl)amino)-3-oxopropyl)-4,6-dihydroxybenzoatemethyl 3-chloro-2-{2-[(2,5-dihydroxy-4-methoxyphenyl)carbamoyl]ethyl}-4,6-dihydroxybenzoate
02
Targets
HSP90AB1 (Heat shock protein HSP 90-beta)
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